A Mencarelli Selected Research

2- methyl- 3- (2- ((4- nitrooxybutyloxy)carbonyl)vinyl)phenyl ursodeoxycholic acid ester

7/2001	NCX-1000, a NO-releasing derivative of ursodeoxycholic acid, selectively delivers NO to the liver and protects against development of portal hypertension.
2/2001	An NO derivative of ursodeoxycholic acid protects against Fas-mediated liver injury by inhibiting caspase activity.

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A Mencarelli Research Topics

Disease

4	Inflammation (Inflammations) 08/2010 - 08/2000
3	Colitis 04/2007 - 11/2001
2	Insulin Resistance 02/2013 - 08/2011
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/2007 - 11/2001
1	Infections 01/2017
1	Opportunistic Infections (Opportunistic Infection) 01/2017
1	Aspergillosis 01/2017
1	Spontaneous Abortion (Miscarriage) 01/2017
1	Invasive Pulmonary Aspergillosis 01/2017
1	Neoplasms (Cancer) 04/2014
1	Cardiotoxicity 02/2013
1	Fibrosis (Cirrhosis) 02/2013
1	Cardiomyopathies (Cardiomyopathy) 02/2013
1	Obesity 02/2013
1	Dyslipidemias (Dyslipidemia) 02/2013
1	Head and Neck Neoplasms (Head and Neck Cancer) 11/2012
1	Non-alcoholic Fatty Liver Disease 08/2011
1	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 08/2011
1	Liver Diseases (Liver Disease) 08/2011
1	Alcoholic Fatty Liver 08/2011
1	Fatty Liver 08/2011
1	Pruritus (Itching) 08/2011
1	Paraganglioma (Paragangliomas) 01/2008
1	Weight Loss (Weight Reduction) 04/2007
1	Diarrhea 04/2007
1	Necrosis 01/2007
1	Portal Hypertension 07/2001
1	Liver Cirrhosis (Hepatic Cirrhosis) 07/2001
1	Autoimmune Hepatitis 02/2001
1	Alzheimer Disease (Alzheimer's Disease) 08/2000
1	Neuroinflammatory Diseases 08/2000

Drug/Important Bio-Agent (IBA)

5	LigandsIBA 02/2013 - 11/2001
3	AcidsIBA 08/2011 - 01/2007
2	sym-trinitrobenzeneIBA 01/2007 - 11/2001
2	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 07/2001 - 02/2001
2	2- methyl- 3- (2- ((4- nitrooxybutyloxy)carbonyl)vinyl)phenyl ursodeoxycholic acid esterIBA 07/2001 - 02/2001
2	CaspasesIBA 02/2001 - 08/2000
1	CalcineurinIBA 01/2017
1	DNA (Deoxyribonucleic Acid)IBA 01/2017
1	Proteins (Proteins, Gene)FDA Link 01/2017
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2017
1	Tacrolimus (Prograf)FDA LinkGeneric 01/2017
1	Fatty Acids (Saturated Fatty Acids)IBA 02/2013
1	Glucose (Dextrose)FDA LinkGeneric 02/2013
1	Insulin (Novolin)FDA Link 02/2013
1	LipidsIBA 02/2013
1	Triglycerides (Triacylglycerol)IBA 02/2013
1	oxidized low density lipoproteinIBA 08/2011
1	Pharmaceutical PreparationsIBA 08/2011
1	Alkaline PhosphataseIBA 08/2011
1	Bile Acids and Salts (Bile Acids)IBA 08/2010
1	Succinate Dehydrogenase (Fumarate Reductase)IBA 01/2008
1	5-amino-2-hydroxybenzoic acid 4-(5-thioxo-5H-(1,2)dithiol-3yl)phenyl esterIBA 04/2007
1	Peroxidase (Myeloperoxidase)IBA 04/2007
1	5- (4- hydroxyphenyl)- 3H- 1,2- dithiole- 3- thioneIBA 04/2007
1	HydrogenIBA 04/2007
1	Mesalamine (Mesalazine)FDA LinkGeneric 04/2007
1	GlucocorticoidsIBA 01/2007
1	Sulfonic AcidsIBA 11/2001
1	Peptides (Polypeptides)IBA 11/2001
1	PAR-2 ReceptorIBA 11/2001
1	EstersIBA 02/2001
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 02/2001
1	Benzoic Acid (Potassium Benzoate)FDA Link 02/2001
1	KetonesIBA 08/2000
1	LipopolysaccharidesIBA 08/2000
1	Cholinergic Agents (Cholinergics)IBA 08/2000
1	ProstaglandinsIBA 08/2000
1	alanylaspartic acidIBA 08/2000

Therapy/Procedure

2	Radiotherapy 04/2014 - 11/2012
2	Therapeutics 04/2007 - 07/2001
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2017
1	Ligation 01/2017
1	Drug Therapy (Chemotherapy) 08/2000